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Article

Clinical significance of FAT1 gene mutation and mRNA expression in patients with head and neck squamous cell carcinoma.

Molecular oncology - 1 Apr 2022

Kim Su Il, Woo Seon Rang, Noh Joo Kyung, Lee Min Kyeong, Lee Young Chan, Lee Jung Woo, Ko Seong-Gyu, Eun Young-Gyu

Abstract excerpt

The FAT1 gene functions as a tumor suppressor or promoter and remains incompletely understood. We examined the clinical significance of FAT1 in head and neck squamous cell carcinoma (HNSCC) using four publicly available HNSCC cohorts and one HNSCC cohort enrolled at a tertiary medical center. We developed FAT1 signatures reflecting FAT1 mutations and mRNA expression using one cohort. Patients with HNSCC were...

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Identifiers

PMID: 34939311
DOI: 10.1002/1878-0261.13171
PMCID: PMC9019907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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