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Article

The mutational spectrum of squamous-cell carcinoma of the head and neck: targetable genetic events and clinical impact.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Oct 2014

Mountzios G, Rampias T, Psyrri A

Abstract excerpt

Squamous-cell cancer of the head and neck (SCCHN) represents a heterogeneous disease entity, with various etiological factors implicated in the genesis of distinct molecular subsets of tumors, which exhibit different biological and clinical behavior. Treatment of SCCHN is expected to change in the next decade as targeted therapies continue to make strides. Recently, next-generation sequencing studies conducted on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Squamous Cell Carcinoma of Head and Neck

Source

Identifiers

PMID: 24718888
DOI: 10.1093/annonc/mdu143

Genes

CASP8
CCND1
FAT1
HRAS
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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