Article

Multi-response Mendelian randomization: Identification of shared and distinct exposures for multimorbidity and multiple related disease outcomes

2023-02-03

Abstract excerpt

The existing framework of Mendelian randomization (MR) infers the causal effect of one or multiple exposures on one single outcome. It is not designed to jointly model multiple outcomes, as would be necessary to detect causes of more than one outcome and would be relevant to model multimorbidity or other related disease outcomes. Here, we introduce Multi-response Mendelian randomization (MR 2 ), a novel MR method...

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Literature Corpus work: f9fbe5bf-65ea-541f-a5c3-b7f4ed80fcff
DOI: 10.1101/2023.02.01.526689

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