Article
The Association Between Runx Signaling and Craniofacial Development and Disease.
Current osteoporosis reports - 1 Feb 2022
Yamashiro Takashi, Kurosaka Hiroshi, Inubush Toshihiro
Abstract excerpt
PURPOSE OF REVIEW: The Runx family genes (Runx1, Runx2, Runx3, and Cbfb) are important transcriptional regulators in the development of various tissues. We herein highlight the roles of the Runx family genes in morphogenesis in the craniofacial regions and in the pathogenesis of congenital morphological problems in these regions. RECENT FINDINGS: A recent analysis using conditional Runx mutant animals and a human...
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