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Article

Genetics and signaling mechanisms of orofacial clefts

15 Jul 2020

Abstract excerpt

Craniofacial development involves several complex tissue movements including several fusion processes to form the frontonasal and maxillary structures, including the upper lip and palate. Each of these movements are controlled by many different factors that are tightly regulated by several integral morphogenetic signaling pathways. Subject to both genetic and environmental influences, interruption at nearly any...

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PMID: 32666711
DOI: 10.1002/bdr2.1754

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