Article

Exosome Load Increases Systemically and Mediates Pro-tumoral M2 Macrophage Polarization in Lymphoma

2023-04-05

Abstract excerpt

Macrophages are the key effector cells of innate immunity which show two polarized states: M1, classically activated and M2, alternatively activated. Tumor-associated macrophages (TAMs) which usually show M2 polarization, are immunosuppressive cells that enhance tumor metastasis and invasion. Also, enrichment of TAMs is known to be closely associated with poor prognosis of cancer patients. Therefore, TAMs are cons...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e61476f7-2338-5ccb-a097-3d46897f2e7f
DOI: 10.20944/preprints202304.0062.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exosome Load Increases Systemically and Mediates Pro-tumoral M2 Macrophage Polarization in LymphomaDOI 10.20944/preprints202304.0062.v1Read

Tumor-derived exosomes in the regulation of macrophage polarization.Semantic proximity Read

Diffuse large B-cell lymphoma-derived exosomes push macrophage polarization toward M2 phenotype via GP130/STAT3 signaling pathway.Semantic proximity Read

Exosome Function: From Tumor Immunology to Pathogen BiologySemantic proximity Read

Exosomal miRNAs-mediated macrophage polarization and its potential clinical application.Semantic proximity Read

Diffuse large B cell lymphoma-derived extracellular vesicles educate macrophages to promote tumours progression by increasing PGC-1β.Semantic proximity Read

[Influencing Factors and Significance of Tumor-associated Macrophage Polarization in Tumor Microenvironment].Semantic proximity Read

Biology, Pathophysiological Role, and Clinical Implications of Exosomes: A Critical AppraisalSemantic proximity Read

Exosomes and Extracellular Vesicles in Myeloid Neoplasia: The Multiple and Complex Roles Played by These “Magic Bullets”Semantic proximity Read

Roles of Cancer Exosomes in Immunosuppression and Immune EvasionSemantic proximity Read

Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting.Semantic proximity Read

Tumor-derived exosomes and their application in cancer treatmentSemantic proximity Read

Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphomaSemantic proximity Read