Back to search

Article

Single nucleotide polymorphisms of the <i>c-MYC</i> gene’s relationship with formation of Burkitt’s lymphoma using bioinformatics analysis

2018-10-24

Abstract excerpt

Burkitt’s lymphoma (BL) is an aggressive form of non-Hodgkin lymphoma, originates from germinal center B cells, MYC gene (MIM ID 190080) is an important proto-oncogene transcriptional factor encoding a nuclear phosphoprotein for central cellular processes. Dysregulated expression or function of c-MYC is one of the most common abnormalities in BL. This study focused on the investigation of the possible role of sing...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0786461e-1aaf-5cb7-83a1-e5330e5ddd74
DOI
10.1101/450783
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Single nucleotide polymorphisms of the <i>c-MYC</i> gene’s relationship with formation of Burkitt’s lymphoma using bioinformatics analysisDOI 10.1101/450783
Functional and structural analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in the MYB oncoproteins associated with human cancer.Semantic proximity
Bio-informatic Analysis of Missense Single Nucleotide Polymorphisms (SNPs) in Human CD38 Gene Associated with B-Chronic Lymphocytic LeukemiaSemantic proximity
In-silico screening of cancer associated mutation on PLK1 protein and its structural consequences.Semantic proximity
A computational in silico approach to predict high-risk coding and non-coding SNPs of human PLCG1 gene.Semantic proximity
MYCbase: a database of functional sites and biochemical properties of Myc in both normal and cancer cells.Semantic proximity
Functional multigenic variations associated with hodgkin lymphoma.Semantic proximity
Protein-truncating and rare missense variants in<i>ATM</i>and<i>CHEK2</i>and associations with cancer in UK Biobank whole-exome sequenced dataSemantic proximity
Computational Modeling of Chromoanagenesis- or Chromothripsis-Induced SNPs in Antiapoptotic Genes: Their Impact on Protein Structure and Function.Semantic proximity
Investigating the pathogenic SNPs in BLM helicase and their biological consequences by computational approach.Semantic proximity
Mutability of Druggable Kinases and Pro-inflammatory Cytokines by Their Proximity to Telomeres and A+T ContentSemantic proximity
In silico analysis of Missense Variants in Human MPL Gene Associated with Essential ThrombocythemiaSemantic proximity
<i>In silico</i> analysis of <i>CDC73</i> gene revealing 11 novel SNPs associated with Jaw Tumor SyndromeSemantic proximity
Select a neighboring publication to make it the new centre.