Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis

22 Jun 2017

Abstract excerpt

Limitless cell proliferation, evasion from apoptosis, dedifferentiation, metastatic spread and therapy resistance: all these properties of a cancer cell contribute to its malignant phenotype and affect patient outcome. MYBL2 (alias B-Myb) is a transcription factor of the MYB transcription factor family and a physiological regulator of cell cycle progression, cell survival and cell differentiation. When...

Topics

Join the communities discussing this publication.

Cancer-related Molecular Pathways
Microtubule and mitosis dynamics
Ubiquitin and proteasome pathways

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28640249
DOI: 10.1038/cddis.2017.244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesisPMID 28640249Read ↗

MYBL2 amplification in breast cancer: Molecular mechanisms and therapeutic potential.Semantic proximity Read ↗

Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogeneSemantic proximity Read ↗

Association between B‑Myb proto‑oncogene and the development of malignant tumors (Review)Semantic proximity Read ↗

MYB oncoproteins: emerging players and potential therapeutic targets in human cancerSemantic proximity Read ↗

B-Myb protein in cellular proliferation, transcription control, and cancer: Latest developmentsSemantic proximity Read ↗

MYBL2 promotes cell proliferation and inhibits cell apoptosis via PI3K/AKT and BCL2/BAX/Cleaved-caspase-3 signaling pathway in gastric cancer cellsSemantic proximity Read ↗

MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3Semantic proximity Read ↗

Actin-binding Rho activating C-terminal like (ABRACL) transcriptionally regulated by MYB proto-oncogene like 2 (MYBL2) promotes the proliferation, invasion, migration and epithelial-mesenchymal transition of breast cancer cellsSemantic proximity Read ↗

Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYBSemantic proximity Read ↗

MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia.Semantic proximity Read ↗

Functional and structural analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in the MYB oncoproteins associated with human cancer.Semantic proximity Read ↗

The role of Bach2 in regulating CD8 + T cell development and functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.