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Article

Predicted Epitope Abundance Supports Vaccine-Induced Cytotoxic Protection Against SARS-CoV-2 Variants of Concern.

Frontiers in immunology - 1 Jan 2021

Martín-Galiano Antonio J, Díez-Fuertes Francisco, McConnell Michael J, López Daniel

Abstract excerpt

The effect of emerging SARS-CoV-2 variants on vaccine efficacy is of critical importance. In this study, the potential impact of mutations that facilitate escape from the cytotoxic cellular immune response in these new virus variants for the 551 most abundant HLA class I alleles was analyzed. Computational prediction showed that most of these alleles, that cover >90% of the population, contain enough epitopes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, MHC Class I

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Source

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Identifiers

PMID: 34899692
DOI: 10.3389/fimmu.2021.732693
PMCID: PMC8656262

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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