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Article

Predicted HLA Class I and Class II Epitopes From Licensed Vaccines Are Largely Conserved in New SARS-CoV-2 Omicron Variant of Concern.

Frontiers in immunology - 1 Jan 2022

López Daniel

Abstract excerpt

The potential effect of emerging SARS-CoV-2 variants on vaccine efficacy is an issue of critical importance. In this study, the possible impact of mutations that facilitate virus escape from the cytotoxic and the helper cellular immune responses in the new SARS-CoV-2 Omicron variant of concern was analyzed for the 551 and 41 most abundant HLA class I and II alleles, respectively. Computational prediction showed...

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Share to COVID-19
Share to Epitopes, T-Lymphocyte
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Immunity, Cellular

Share to Immunogenicity, Vaccine

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 35154154
DOI: 10.3389/fimmu.2022.832889
PMCID: PMC8831693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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