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Article

Automating the Design of Cancer Specific DNA Probes Using Computational Algorithms.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Nov 2021

Zhang Jiacheng, Alexandrou George, Toumazou Chris, Kalofonou Melpomeni

Abstract excerpt

This paper introduces a novel Python script which automates the design process of cancer variant-specific DNA probes, based on the amplification method LAMP (Loop-Mediated Isothermal Amplification). With just an input of the DNA sequence and the mutation base location, the script outputs suggestions of two best fitting primer sets for a given target, together with an estimated working efficiency. The script also...

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PMID: 34891648
DOI: 10.1109/EMBC46164.2021.9630589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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