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Robust dPCR Hyper-Plexing Approach by Color Combination for Detection of 17 ESR1 Mutations in Breast Cancer Patient Samples.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Ursuegui Sylvain, Donzier Julie, Jovelet Cécile, Fradet Etienne, Dangla Rémi

Abstract excerpt

Digital PCR has seen increasing adoption in recent years since it overcomes most of the main technical limitations of real-time PCR. However, the level of multiplexing remains limited when facing the need to develop approaches that can detect multiple targets in a single reaction with a high sensitivity to obtain a more complete genetic characterization of samples. This need concerns most molecular biology...

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Identifiers

PMID: 41073861
DOI: 10.1007/978-1-0716-4767-7_7

Genes

ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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