Article

Multi-feature Classification to Improve Colorimetric Loop-Mediated Isothermal Amplification Fidelity

2026-06-08

Abstract excerpt

Loop-mediated isothermal amplification (LAMP) is a cost-effective and portable assay technique for performing nucleic acid-based diagnostics in the field whose adoption is hindered by design and reproducibility issues. This is due to a complex primer design process that fine-tunes parameters across 6-8 binding regions. The likelihood of assay success depends on satisfying thermodynamic and secondary structure cons...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5e0269df-64d6-5255-9868-f29c7a5c6f22
DOI: 10.64898/2026.06.03.728514

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-feature Classification to Improve Colorimetric Loop-Mediated Isothermal Amplification FidelityDOI 10.64898/2026.06.03.728514Read

Hierarchical Bayesian modeling identifies key considerations in the development of quantitative loop-mediated isothermal amplification assaysSemantic proximity Read

Using Machine Learning Models to Predict the Impact of Template Mismatches on Polymerase Chain Reaction (PCR) Assay PerformanceSemantic proximity Read

Development of loop-mediated isothermal amplification (LAMP) assays using five primers reduces the false-positive rate in COVID-19 diagnosisSemantic proximity Read

A data-driven consensus framework for Ct interpretation in real-world multi-assay qPCR diagnosticsSemantic proximity Read

Universal Digital High Resolution Melt for the detection of pulmonary mold infectionsSemantic proximity Read

Analysis of a Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) for yellow fever diagnosticSemantic proximity Read

Trainable high resolution melt curve machine learning classifier for large-scale reliable genotyping of sequence variants.Semantic proximity Read

Automating the Design of Cancer Specific DNA Probes Using Computational Algorithms.Semantic proximity Read

Loop-Mediated Isothermal Amplification (LAMP), An Innovation in Gene Amplification: Bridging the Gap in Molecular Diagnostics; A ReviewSemantic proximity Read

A reverse transcription loop-mediated isothermal amplification assay optimized to detect multiple HIV subtypes.Semantic proximity Read

Machine learning based DNA melt curve profiling enables automated novel genotype detection.Semantic proximity Read

Nested Machine Learning Facilitates Increased Sequence Content for Large-Scale Automated High Resolution Melt Genotyping.Semantic proximity Read