Article
Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex-specific and lifestyle factors specific associations.
International journal of cancer - 1 May 2022
Huang Yuhan, Hua Xinwei, Labadie Julia D, Harrison Tabitha A, Dai James Y, Lindstrom Sara, Lin Yi, Berndt Sonja I, Buchanan Daniel D, Campbell Peter T, Casey Graham, Gallinger Steven J, Gunter Marc J, Hoffmeister Michael, Jenkins Mark A, Sakoda Lori C, Schoen Robert E, Diergaarde Brenda, Slattery Martha L, White Emily, Giles Graham, Brenner Hermann, Chang-Claude Jenny, Joshi Amit, Ma Wenjie, Pai Rish K, Chan Andrew T, Peters Ulrike, Newcomb Polly A
Abstract excerpt
Elevated blood levels of C-reactive protein (CRP) have been linked to colorectal cancer (CRC) survival. We evaluated genetic variants associated with CRP levels and their interactions with sex and lifestyle factors in association with CRC-specific mortality. Our study included 16 142 CRC cases from the International Survival Analysis in Colorectal Cancer Consortium. We identified 618 common single nucleotide...
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