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Article

Plasma C-reactive protein, genetic risk score, and risk of common cancers in the Atherosclerosis Risk in Communities study.

Cancer causes & control : CCC - 1 Dec 2013

Prizment Anna E, Folsom Aaron R, Dreyfus Jill, Anderson Kristin E, Visvanathan Kala, Joshu Corinne E, Platz Elizabeth A, Pankow James S

Abstract excerpt

PURPOSE: Many studies, including the Atherosclerosis Risk in Communities (ARIC) cohort, reported a positive association between plasma C-reactive protein (CRP)-a biomarker of low-grade chronic inflammation-and colorectal cancer risk, although it is unclear whether the association is causal. Our aims were to assess the associations of a CRP genetic risk score (CRP-GRS) created from single-nucleotide polymorphisms...

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Identifiers

PMID: 24036889
DOI: 10.1007/s10552-013-0285-y
PMCID: PMC3836434

Genes

CRP
APOC1
LEPR

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