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Article

Evaluation of genetic variants in association with colorectal cancer risk and survival in Asians.

International journal of cancer - 15 Sept 2017

Wang Nan, Lu Yingchang, Khankari Nikhil K, Long Jirong, Li Hong-Lan, Gao Jing, Gao Yu-Tang, Xiang Yong-Bing, Shu Xiao-Ou, Zheng Wei

Abstract excerpt

Genome-wide association studies (GWAS) have identified over 40 genetic loci associated with colorectal cancer (CRC) risk. The association of single nucleotide polymorphisms (SNPs) at these loci with CRC risk and survival has not been adequately evaluated in East Asians. GWAS-identified CRC risk variants were used to construct weighted genetic risk scores (GRSs). We evaluated these GRSs in association with CRC...

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Identifiers

PMID: 28567967
DOI: 10.1002/ijc.30812
PMCID: PMC5524202

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