Article
Recurrence of Graves' Disease: What Genetics of HLA and PTPN22 Can Tell Us.
Frontiers in endocrinology - 1 Jan 2021
Vejrazkova Daniela, Vcelak Josef, Vaclavikova Eliska, Vankova Marketa, Zajickova Katerina, Vrbikova Jana, Duskova Michaela, Pacesova Petra, Novak Zdenek, Bendlova Bela
Abstract excerpt
Background: Approximately half of patients diagnosed with Graves' disease (GD) relapse within two years of thyreostatic drug withdrawal. It is then necessary to decide whether to reintroduce conservative treatment that can have serious side effects, or to choose a radical approach. Familial forms of GD indicate a significant genetic component. Our aim was to evaluate the practical benefits of HLA and PTPN22...
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