Article
Cytotoxic T lymphocyte-associated molecule-4 gene polymorphism and hyperthyroid Graves' disease relapse after antithyroid drug withdrawal: a follow-up study.
The Journal of clinical endocrinology and metabolism - 1 Jul 2007
Wang Pei-Wen, Chen I-Ya, Liu Rue-Tsuan, Hsieh Ching-Jung, Hsi Edward, Juo Suh-Hang Hank
Abstract excerpt
CONTEXT: We previously showed an association between the exon1 +49 A/G single nucleotide polymorphism (SNP) and the relapse of Graves' disease (GD). The G allele was associated with early relapse. OBJECTIVE: In this follow-up study, we sought to replicate the result by genotyping nine additional polymorphisms and recruiting another 60 GD patients. DESIGN AND PARTICIPANTS: The GD patients were divided into three...
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