Article
DQA2 U allele: a genetic marker for relapse of Graves' disease.
Clinical endocrinology - 1 Feb 1990
Ratanachaiyavong S, Gunn C A, Bidwell E A, Darke C, Hall R, McGregor A M
Abstract excerpt
The association of HLA-DR3 with Graves' disease in Caucasoids is well established but its significance is unclear and its clinical value as a predictive parameter for relapse after a course of antithyroid drug therapy is controversial. We have further investigated the predictive value at the genomic level in 51 patients with Graves' disease who were treated with a 6-month course of carbimazole and followed up for...
Topics
- Alleles
- Blotting, Southern
- Carbimazole
- Female
- Genes, MHC Class II
- Genetic Markers
- Graves Disease
- HLA-DR3 Antigen
- Humans
- Male
- Polymorphism, Restriction Fragment Length
