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Article

Vasorin deficiency leads to cardiac hypertrophy by targeting MYL7 in young mice

2 Dec 2021

Abstract excerpt

Abstract Vasorin (VASN) is an important transmembrane protein associated with development and disease. However, it is not clear whether the death of mice with VASN deficiency (VASN−/−) is related to cardiac dysfunction. The aim of this research was to ascertain whether VASN induces pathological cardiac hypertrophy by targeting myosin light chain 7 (MYL7). VASN−/− mice were produced by CRISPR/Cas9 technology and...

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PMID: 34854218
DOI: 10.1111/jcmm.17034

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