Article
polo encodes a protein kinase homolog required for mitosis in Drosophila.
Genes & development - 1 Dec 1991
Llamazares S, Moreira A, Tavares A, Girdham C, Spruce B A, Gonzalez C, Karess R E, Glover D M, Sunkel C E
Abstract excerpt
We show that mutation in polo leads to a variety of abnormal mitoses in Drosophila larval neuroblasts. These include otherwise normal looking mitotic spindles upon which chromosomes appear overcondensed; normal bipolar spindles with polyploid complements of chromosomes; bipolar spindles in which...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA
- DNA Transposable Elements
- Drosophila
- Drosophila Proteins
- Female
- Larva
- Male
- Mitosis
- Molecular Sequence Data
- Mutation
- Protein Kinases
- Protein Serine-Threonine Kinases
- Sequence Homology, Nucleic Acid
- Spindle Apparatus