Article
Genetic architecture modulates diet-induced hepatic mRNA and miRNA expression profiles in Diversity Outbred mice.
Genetics - 14 Jul 2021
Que Excel, James Kristen L, Coffey Alisha R, Smallwood Tangi L, Albright Jody, Huda M Nazmul, Pomp Daniel, Sethupathy Praveen, Bennett Brian J
Abstract excerpt
Genetic approaches in model organisms have consistently demonstrated that molecular traits such as gene expression are under genetic regulation, similar to clinical traits. The resulting expression quantitative trait loci (eQTL) have revolutionized our understanding of genetic regulation and identified numerous candidate genes for clinically relevant traits. More recently, these analyses have been extended to...
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