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Article

Mechanisms of viral inflammation and disease in humans.

Science (New York, N.Y.) - 26 Nov 2021

Casanova Jean-Laurent, Abel Laurent

Abstract excerpt

Disease and accompanying inflammation are uncommon outcomes of viral infection in humans. Clinical inflammation occurs if steady-state cell-intrinsic and leukocytic immunity to viruses fails. Inflammation attests to the attempts of newly recruited and activated leukocytes to resolve infection in the blood or tissues. In the confusing battle between a myriad of viruses and cells, studies of human genetics can...

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Identifiers

PMID: 34822298
DOI: 10.1126/science.abj7965
PMCID: PMC8697421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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