Infection and autoinflammation in inborn errors of immunity: brothers in arms.

doi:10.1016/j.coi.2021.08.004

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

Infection and autoinflammation in inborn errors of immunity: brothers in arms.

Current opinion in immunology - 1 Oct 2021

Delafontaine Selket, Meyts Isabelle

Abstract excerpt

The binary view of inborn errors of immunity classified as either autoinflammatory conditions or primary immunodeficiency in the strict sense, that is, increased susceptibility to infection is challenged by the description of recent inborn errors of immunity (IEI) triggers leading to activation and disruption of cell death pathways, play a major part in the pathophysiology of infection and autoinflammation. In...

Topics

Alleles
Animals
Autoantibodies
Autoimmunity
Biomarkers
Endoplasmic Reticulum Stress
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Immunity
Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Inflammation

Interferon Type I

Mutation

Organ Specificity

Phenotype

Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 34543865
DOI: 10.1016/j.coi.2021.08.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Infection and autoinflammation in inborn errors of immunity: brothers in arms.PMID 34543865Read ↗

Inborn errors of immunity: A field without frontiers.Semantic proximity Read ↗

Infections in Inborn Errors of Immunity with Combined Immune Deficiency: A ReviewSemantic proximity Read ↗

Inborn errors of immunity: an expanding universe of disease and genetic architectureSemantic proximity Read ↗

Inborn Errors of Immunity: how to diagnose them?Semantic proximity Read ↗

Lessons learned from the study of human inborn errors of innate immunity.Semantic proximity Read ↗

Approach to Diagnosing Inborn Errors of Immunity.Semantic proximity Read ↗

Inborn errors of immunity—recent advances in research on the pathogenesisSemantic proximity Read ↗

Neuroinflammation Associated With Inborn Errors of Immunity.Semantic proximity Read ↗

The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies.Semantic proximity Read ↗

Updates on new monogenic inborn errors of immunity.Semantic proximity Read ↗

Inborn errors of immunity to infection: the rule rather than the exception.Semantic proximity Read ↗

The Ever-Increasing Array of Novel Inborn Errors of Immunity: an Interim Update by the IUIS Committee.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.