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Article

A conditional autoregressive model for genetic association analysis accounting for genetic heterogeneity.

Statistics in medicine - 10 Feb 2022

Shen Xiaoxi, Wen Yalu, Cui Yuehua, Lu Qing

Abstract excerpt

Converging evidence from genetic studies and population genetics theory suggest that complex diseases are characterized by remarkable genetic heterogeneity, and individual rare mutations with different effects could collectively play an important role in human diseases. Many existing statistical models for association analysis assume homogeneous effects of genetic variants across all individuals, and could be...

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Identifiers

PMID: 34811777
DOI: 10.1002/sim.9257
PMCID: PMC8792507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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