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Article

Surveillance and Surgical Considerations in Hereditary Diffuse Gastric Cancer.

Gastrointestinal endoscopy clinics of North America - 1 Jan 2022

Gamble Lauren A, Davis Jeremy L

Abstract excerpt

Inactivating germline variants in the CDH1 tumor suppressor gene cause the hereditary diffuse gastric cancer syndrome. Total gastrectomy is recommended for prevention, although it is associated with adverse outcomes and chronic health risks. Gastric cancer surveillance is an alternative to surgery; however, upper gastrointestinal endoscopy is limited by poor sensitivity. Cancer surveillance requires accurate...

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Identifiers

PMID: 34798984
DOI: 10.1016/j.giec.2021.08.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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