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Article

Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms.

BMC microbiology - 20 Nov 2021

Torres Diana Albertos, Seth-Smith Helena M B, Joosse Nicole, Lang Claudia, Dubuis Olivier, Nüesch-Inderbinen Magdalena, Hinic Vladimira, Egli Adrian

Abstract excerpt

BACKGROUND: Colistin is used against multi-drug resistant pathogens, yet resistance emerges through dissemination of plasmid-mediated genes (mcr) or chromosomal mutation of genes involved in lipopolysaccharide synthesis (i.e. mgrB, phoPQ, pmrCAB). Phenotypic susceptibility testing is challenging due to poor diffusion of colistin in agar media, leading to an underestimation of resistance. Performance of five...

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Identifiers

PMID: 34798825
DOI: 10.1186/s12866-021-02388-8
PMCID: PMC8605564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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