Article
A simple phenotypic method for screening of MCR-1-mediated colistin resistance.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Feb 2018
Coppi M, Cannatelli A, Antonelli A, Baccani I, Di Pilato V, Sennati S, Giani T, Rossolini G M
Abstract excerpt
OBJECTIVES: To evaluate a novel method, the colistin-MAC test, for phenotypic screening of acquired colistin resistance mediated by transferable mcr-1 resistance determinants, based on colistin MIC reduction in the presence of dipicolinic acid (DPA). METHODS: The colistin-MAC test consists in a broth microdilution method, in which colistin MIC is tested in the absence or presence of DPA (900 μg/mL). Overall, 74...
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