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MgrB Alterations Mediate Colistin Resistance in Klebsiella pneumoniae Isolates from Iran

18 Dec 2017

Abstract excerpt

Colistin is one of the last-resort therapeutic agents to combat multidrug-resistant Gram-negative bacteria (GNB) including Klebsiella pneumoniae. Although it happens rarely, resistance to colistin has been reported for several GNB. A total of 20 colistin resistant (col-R) and three colistin susceptible (col-S) clinical isolates of K. pneumoniae were studied to explore the underlying mechanisms of colistin...

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PMID: 29326662
DOI: 10.3389/fmicb.2017.02470

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