Article
Inherent colistin resistance in genogroups of the Enterobacter cloacae complex: epidemiological, genetic and biochemical analysis from the BSAC Resistance Surveillance Programme.
The Journal of antimicrobial chemotherapy - 1 Sept 2020
Mushtaq Shazad, Reynolds Rosy, Gilmore Michael C, Esho Olubukola, Adkin Rachael, García-Romero Inmaculada, Chaudhry Aiysha, Horner Carolyne, Bartholomew Toby L, Valvano Miguel A, Dry Magdalena, Murray John, Pichon Bruno, Livermore David M
Abstract excerpt
BACKGROUND: Polymyxins have re-entered use against problem Gram-negative bacteria. Resistance rates are uncertain, with estimates confounded by selective testing. METHODS: The BSAC Resistance Surveillance Programme has routinely tested colistin since 2010; we reviewed data up to 2017 for relevant Enterobacterales (n = 10 914). Unexpectedly frequent resistance was seen among the Enterobacter cloacae complex...
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