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Article

Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study.

Cancer prevention research (Philadelphia, Pa.) - 1 Feb 2022

Uson Junior Pedro Ls, Kunze Katie L, Golafshar Michael A, Riegert-Johnson Douglas, Boardman Lisa, Borad Mitesh J, Ahn Daniel, Sonbol Mohamad B, Faigel Douglas O, Fukami Norio, Pannala Rahul, Barrus Kathleen, Mountjoy Luke, Esplin Edward D, Nussbaum Robert L, Stewart A Keith, Bekaii-Saab Tanios, Samadder N Jewel

Abstract excerpt

Data from germline testing in unselected patients with hepatobiliary cancers are limited. Identification of germline predisposition can have important implications on cancer treatment and family counseling. To determine prevalence of pathogenic germline variants (PGV) in patients with hepatobiliary cancer, we undertook a prospective multi-site study of germline sequencing using a >80-gene next-generation...

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Identifiers

PMID: 34782326
DOI: 10.1158/1940-6207.CAPR-21-0189
PMCID: PMC9662853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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