Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline alterations in patients with biliary tract cancers: A spectrum of significant and previously underappreciated findings

3 Feb 2020

Abstract excerpt

BACKGROUND: With limited information on germline mutations in biliary tract cancers, this study performed somatic and germline testing for patients at Memorial Sloan Kettering Cancer Center with known biliary tract carcinoma with the aim of determining the frequency and range of pathogenic germline alterations (PGAs). METHODS: Patients with biliary tract carcinoma were consented for somatic tumor and matched...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Gallbladder and Bile Duct Disorders
Share to Pediatric Hepatobiliary Diseases and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32012241
DOI: 10.1002/cncr.32740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline alterations in patients with biliary tract cancers: A spectrum of significant and previously underappreciated findingsPMID 32012241Read ↗

Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancerSemantic proximity Read ↗

Molecular profile of BRCA-mutated biliary tract cancersSemantic proximity Read ↗

Clinical Implications of BRCA Mutations in Advanced Biliary Tract Cancer.Semantic proximity Read ↗

Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.Semantic proximity Read ↗

Germline Pathogenic Variants in Patients With Pancreatic and Periampullary Cancers.Semantic proximity Read ↗

Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targetsSemantic proximity Read ↗

Mutational spectrum and precision oncology for biliary tract carcinoma.Semantic proximity Read ↗

Comparative analysis of genomic profiles and clinical outcomes in cholangiocarcinoma and gallbladder cancer.Semantic proximity Read ↗

Genomic Profiling of Biliary Tract Cancers and Implications for Clinical Practice.Semantic proximity Read ↗

Germline testing and genetic counseling in biliary tract cancer: an operative proposal to improve the state of art.Semantic proximity Read ↗

Biliary tract cancers: epidemiology, molecular pathogenesis and genetic risk associations.Semantic proximity Read ↗

Hereditary cancer variants and homologous recombination deficiency in biliary tract cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.