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Article

Germline Cancer Testing in Unselected Patients with Gastric and Esophageal Cancers: A Multi-center Prospective Study.

Digestive diseases and sciences - 1 Nov 2022

Uson P L S, Kunze K L, Golafshar M A, Botrus G, Riegert-Johnson D, Boardman L, Borad M J, Ahn D, Sonbol M B, Kahn A, Klint M, Esplin E D, Nussbaum R L, Stewart A K, Bekaii-Saab T, Samadder N J

Abstract excerpt

BACKGROUND AND AIMS: To determine prevalence and clinical utility of pathogenic germline variants (PGV) in gastric and esophageal cancer patients using universal genetic testing approach. METHODS: We undertook a prospective study of germline sequencing using an > 80 gene next-generation sequencing platform among patients with gastric and esophageal cancers receiving care at Mayo Clinic Cancer Center between April...

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Identifiers

PMID: 35122589
DOI: 10.1007/s10620-022-07387-x
PMCID: PMC9587949

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