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Article

Prevalence of Germline Findings Among Tumors From Cancer Types Lacking Hereditary Testing Guidelines.

JAMA network open - 2 May 2022

Yap Timothy A, Ashok Arya, Stoll Jessica, Mauer Elizabeth, Nepomuceno Vanessa M, Blackwell Kimberly L, Garber Judy E, Meric-Bernstam Funda

Abstract excerpt

Importance: Germline testing guidelines are suggested for specific disease types or a family history of cancer, yet alterations are found in cancer types in which germline testing is not routinely indicated. The clinical role of identifying germline variants in these populations is valuable to patients and their at-risk relatives. Objective: To evaluate the prevalence of germline findings in patients undergoing...

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Identifiers

PMID: 35594047
DOI: 10.1001/jamanetworkopen.2022.13070
PMCID: PMC9123503

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