Article
The effect of paraoxonase 1 (PON1) gene polymorphisms T(-107)C and L55M and diet composition on serum PON1 activity in women.
Archives of endocrinology and metabolism - 24 Nov 2021
Zanini Bianka Machado, Burkert Leticia, Dos Santos Fabiola Goettem, Masternak Michal M, Crespo-Ribeiro José Augusto, Barros Carlos Castilho, Valle Sandra Costa, Schneider Augusto
Abstract excerpt
OBJECTIVE: The aim of this study was to evaluate the serum activity of PON1 in women according to SNPs L55M and T-107C and diet composition. METHODS: Blood and serum samples from 26 women were used. DNA extraction, PCR and digestion with restriction enzymes of the PCR fragment were performed for genotyping the PON1 SNPs T-107C and L55M. Serum PON1 activity was measured in a single time point. Patients completed...
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