Article
Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2000
Turgut Cosan Didem, Colak E, Saydam F, Yazıcı H U, Degirmenci I, Birdane A, Colak E, Gunes H V
Abstract excerpt
Human serum paraoxonase 1 (PON1) is carried by high-density lipoprotein in blood circulation and is shown to be effective in preventing oxidized phospholipids carried by low-density lipoprotein particles, thus it acts as an antioxidant. Polymorphism in this gene has been investigated for many metabolic diseases, but it is not thought to be a genetic risk factor for essential hypertension. The aim of this study...
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