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Article

Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population.

Cell biochemistry and function - 1 Dec 2009

Demirdöğen Birsen Can, Demirkaya Seref, Türkanoğlu Aysun, Bek Semai, Arinç Emel, Adali Orhan

Abstract excerpt

BACKGROUND: Paraoxonase1 (PON1) is protective against the development of atherosclerosis, a risk factor for ischemic stroke. PON1 gene has one promoter region (-107T/C) and two coding region (192Q/R and 55L/M) polymorphisms that affect the levels and catalytic efficiency of the enzyme, respectively. In this study, we aimed to determine the importance of -107T/C, 192Q/R and 55L/M polymorphisms of PON1 gene and...

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Identifiers

PMID: 19902425
DOI: 10.1002/cbf.1607

Genes

PON1

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