Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of spike mutations following antibody treatment in two immunocompromised patients with persistent COVID-19 infection.

Journal of medical virology - 1 Mar 2022

Bronstein Yotam, Adler Amos, Katash Haytham, Halutz Ora, Herishanu Yair, Levytskyi Katia

Abstract excerpt

Immunocompromised patients have an increased risk of persistent COVID-19 disease. We report here the clinical course of two patients with hematologic malignancies hospitalized due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In both patients, viral evolution including new spike gene mutations that occurred following treatment with anti-SARS-CoV-2 antibodies preparations, including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal, Humanized
Share to Antibodies, Neutralizing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Viral

Share to COVID-19 Drug Treatment

Share to Immunization, Passive

Share to Immunocompromised Host

Share to SARS-CoV-2

Share to Spike Glycoprotein, Coronavirus

Source

Open in PubMed Open full text

Identifiers

PMID: 34755363
DOI: 10.1002/jmv.27445
PMCID: PMC8661643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of spike mutations following antibody treatment in two immunocompromised patients with persistent COVID-19 infection.PMID 34755363Read ↗

Clinical and Virological Outcome of Monoclonal Antibody Therapies Across SARS-CoV-2 Variants in 245 Immunocompromised Patients: A Multicenter Prospective Cohort Study.Semantic proximity Read ↗

SARS-CoV-2 Variants in Immunocompromised Patient Given Antibody MonotherapySemantic proximity Read ↗

SARS-CoV-2 evolution during prolonged infection in immunocompromised patientsSemantic proximity Read ↗

Emergence of multiple SARS-CoV-2 mutations in an immunocompromised hostSemantic proximity Read ↗

Evolution of a globally unique SARS-CoV-2 Spike E484T monoclonal antibody escape mutation in a persistently infected, immunocompromised individualSemantic proximity Read ↗

Emergence of SARS-CoV-2 resistance mutations in a patient who received anti-SARS-COV2 spike protein monoclonal antibodies: a case report.Semantic proximity Read ↗

Spike Gene Evolution and Immune Escape Mutations in Patients with Mild or Moderate Forms of COVID-19 and Treated with Monoclonal Antibodies Therapies.Semantic proximity Read ↗

SARS-CoV-2 evolution and evasion from multiple antibody treatments in a cancer patientSemantic proximity Read ↗

SARS-CoV-2 evolution and immune escape in immunocompromised patients treated with exogenous antibodiesSemantic proximity Read ↗

De novo emergence of SARS-CoV-2 spike mutations in immunosuppressed patients.Semantic proximity Read ↗

Emergence of SARS-CoV-2 Spike Mutations during Prolonged Infection in Immunocompromised Hosts.Semantic proximity Read ↗

SARS-CoV-2 variants from long-term, persistently infected immunocompromised patients have altered syncytia formation, temperature-dependent replication, and serum neutralizing antibody escapeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.