Article
Clinical and Virological Outcome of Monoclonal Antibody Therapies Across SARS-CoV-2 Variants in 245 Immunocompromised Patients: A Multicenter Prospective Cohort Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 14 Jun 2024
Huygens Sammy, GeurtsvanKessel Corine, Gharbharan Arvind, Bogers Susanne, Worp Nathalie, Boter Marjan, Bax Hannelore I, Kampschreur Linda M, Hassing Robert-Jan, Fiets Roel B, Levenga Henriette, Afonso Pedro Miranda, Koopmans Marion, Rijnders Bart J A, Oude Munnink Bas B
Abstract excerpt
BACKGROUND: Immunocompromised patients (ICPs) have an increased risk for a severe and prolonged COVID-19. SARS-CoV-2 monoclonal antibodies (mAbs) were extensively used in these patients, but data from randomized trials that focus on ICPs are lacking. We evaluated the clinical and virological outcome of COVID-19 in ICPs treated with mAbs across SARS-CoV-2 variants. METHODS: In this multicenter prospective cohort...
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