Article
Emergence of SARS-CoV-2 resistance mutations in a patient who received anti-SARS-COV2 spike protein monoclonal antibodies: a case report.
BMC infectious diseases - 7 Dec 2021
Fenaux Honorine, Gueneau Romain, Chaghouri Amal, Henry Benoît, Mouna Lina, Roque-Afonso Anne-Marie, Vauloup-Fellous Christelle
Abstract excerpt
BACKGROUND: To manage severe or potentially severe cases of CoronaVirus Disease 2019 (COVID-19), therapeutic monoclonal antibodies targeting Spike protein of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) have been designed. It has been noted in vitro that upon exposure to these treatments, mutations could be selected. CASE PRESENTATION: We here report the case of an immunosuppressed patient...
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