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Article

Copy number variation of IL17RA gene and its association with the ankylosing spondylitis risk in Iranian patients: a case-control study.

BMC medical genetics - 10 Jul 2020

Aghaei Hamideh, Farhadi Elham, Akhtari Maryam, Shahba Sara, Mostafaei Shayan, Jamshidi Ahmadreza, Poursani Shiva, Mahmoudi Mahdi, Nicknam Mohammad Hossein

Abstract excerpt

BACKGROUND: Ankylosing spondylitis (AS) is considered as a subtype of spondyloarthritis (SpA) that mainly leads to fatigue, stiffness, spinal ankylosis, and impaired physical functions with reduced quality of life. Interleukin (IL)-17A provokes additional inflammatory mediators and recruits immune cells to the inflamed site. IL17 expression increased in various inflammatory disorders including psoriasis,...

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Source

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Identifiers

PMID: 32650733
DOI: 10.1186/s12881-020-01078-y
PMCID: PMC7350761

Genes

IL17RA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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