Article
Influence of TNF and IL17 Gene Polymorphisms on the Spondyloarthritis Immunopathogenesis, Regardless of HLA-B27, in a Brazilian Population.
Mediators of inflammation - 1 Jan 2018
Rocha Loures Marco A, Macedo Luciana C, Reis Denise M, Oliveira Camila F, Meneguetti Jean L, Martines Gabriela F, Neves Janisleya S F, de Souza Eliana, Sell Ana M, Visentainer Jeane E L
Abstract excerpt
BACKGROUND AND OBJECTIVES: Spondyloarthritis (SpA) represents a heterogeneous group of immune-mediated inflammatory diseases that have overlapping clinical features, genetic predisposition, and pathogenic mechanisms. Hence, we investigated, through a case-control study, whether single-nucleotide polymorphisms of TNF and IL17 genes are associated with SpA, ankylosing spondylitis (AS), and psoriatic arthritis (PsA)...
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