Article
An autoregulation loop in fust-1 for circular RNA regulation in Caenorhabditis elegans.
Genetics - 5 Nov 2021
Cao Dong
Abstract excerpt
Many circular RNAs (circRNAs) are differentially expressed in different tissues or cell types, suggestive of specific factors that regulate their biogenesis. Here, taking advantage of available mutation strains of RNA-binding proteins (RBPs) in Caenorhabditis elegans, I performed a screening of circRNA regulation in 13 conserved RBPs. Among them, loss of FUST-1, the homolog of Fused in Sarcoma (FUS), caused...
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