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Article

The important roles and molecular mechanisms of annexin A2 autoantibody in children with nephrotic syndrome

1 Sept 2021

Abstract excerpt

Background: In recent years, B-cell dysfunction has been found to play an important role in the pathogenesis of primary nephrotic syndrome (PNS). B cells play a pathogenic role by secreting antibodies against their target antigens after transforming into plasma cells. Therefore, this study aimed to screen the autoantibodies that cause PNS and explore their pathogenic mechanisms. Methods: Western blotting and mass...

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PMID: 34734004
DOI: 10.21037/atm-21-3988

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