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Article

A Novel Insight into the Role of PLA2R and THSD7A in Membranous Nephropathy

14 Jul 2021

Abstract excerpt

Membranous nephropathy (MN) is an organ-restricted autoimmune disease mainly caused by circulating autoantibodies against podocyte antigens, including the M-type phospholipase A2 receptor (PLA2R) and thrombospondin domain-containing 7A (THSD7A). Antibodies against PLA2R are present in 70%-80% and against THSD7A in 2% of adult patients, which provides a paradigm shift in molecular diagnosis and management...

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PMID: 34337081
DOI: 10.1155/2021/8163298

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