Article
Codon 13 KRAS mutation predicts patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases.
Cancer - 1 Sept 2016
Margonis Georgios A, Kim Yuhree, Sasaki Kazunari, Samaha Mario, Amini Neda, Pawlik Timothy M
Abstract excerpt
BACKGROUND: Investigations regarding the impact of tumor biology after surgical management of colorectal liver metastasis have focused largely on overall survival. We investigated the impact of codon-specific KRAS mutations on the rates and patterns of recurrence in patients after surgery for colorectal liver metastasis (CRLM). METHODS: All patients who underwent curative-intent surgery for CRLM between 2002 and...
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