A critical appraisal of the current landscape of resectable BRAF mutated colorectal liver metastases: a systematic review.

doi:10.21037/cco-23-128

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Article

A critical appraisal of the current landscape of resectable BRAF mutated colorectal liver metastases: a systematic review.

Chinese clinical oncology - 1 Aug 2024

Margonis Georgios Antonios, Wang Jaeyun, Papakonstantinou Dimitris, Beyer Katharina, Kreis Martin E, D'Angelica Michael

Abstract excerpt

BACKGROUND: Patients with surgically resectable BRAF-mutated colorectal liver metastases (CRLM) or limited extrahepatic disease constitute a highly selective subgroup among BRAF-mutated patients, characterized by a more indolent disease biology. This is evident in their suitability for surgical resection. However, initial studies from a decade ago presented a discouraging outlook for these patients, citing early,...

Topics

Humans
Colorectal Neoplasms
Proto-Oncogene Proteins B-raf
Liver Neoplasms
Mutation

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Open in PubMed

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PMID: 38859602
DOI: 10.21037/cco-23-128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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