Article
An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer.
Breast cancer research : BCR - 30 Oct 2021
Scherer Sandra D, Riggio Alessandra I, Haroun Fadi, DeRose Yoko S, Ekiz H Atakan, Fujita Maihi, Toner Jennifer, Zhao Ling, Li Zheqi, Oesterreich Steffi, Samatar Ahmed A, Welm Alana L
Abstract excerpt
BACKGROUND: Metastatic breast cancer (MBC) is incurable, with a 5-year survival rate of 28%. In the USA, more than 42,000 patients die from MBC every year. The most common type of breast cancer is estrogen receptor-positive (ER+), and more patients die from ER+ breast cancer than from any other subtype. ER+ tumors can be successfully treated with hormone therapy, but many tumors acquire endocrine resistance, at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.