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Article

Parkinson's disease-dementia in trans LRP10 and GBA variants: Response to deep brain stimulation.

Parkinsonism & related disorders - 1 Nov 2021

Neri Marcella, Braccia Arianna, Panteghini Celeste, Garavaglia Barbara, Gualandi Francesca, Cavallo Michele Alessandro, Scerrati Alba, Ferlini Alessandra, Sensi Mariachiara

Abstract excerpt

We report on a patient with Parkinson's disease and dementia who underwent DBS with excellent response in motor features; the genotype is heterozygous for a novel LRP10 variant in trans with a GBA variant. He had a more severe phenotype compared to the father who only carries the LRP10 variant.

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PMID: 34710740
DOI: 10.1016/j.parkreldis.2021.10.020

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