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The role of PDGFRA as a therapeutic target in young colorectal cancer patients

26 Oct 2021

Abstract excerpt

BACKGROUND: Young patients with colorectal cancer (CRC) exhibit poor prognoses compared to older patients due to the difficulty in early diagnosis and treatment. However, the underlying molecular characteristics are still unclear. METHODS: We conducted a comprehensive analysis of 49 CRC patients without hereditary CRC using the whole-exome and RNA sequencing with tumor and matched normal samples. A total of 594...

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PMID: 34702313
DOI: 10.1186/s12967-021-03088-7

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